Spinal phospholipase A2 in inflammatory hyperalgesia: Role of the small, secretory phospholipase A2
نویسندگان
چکیده
منابع مشابه
Spinal phospholipase A2 in inflammatory hyperalgesia: role of group IVA cPLA2.
Current work has shown the importance of spinal cyclooxygenase (COX) products in facilitatory processes leading to tissue injury induced hyperalgesia. This cascade must originate with free arachidonic acid (AA) released by the activity of spinal phospholipase A2s (PLA2). In the present work, we studied the role of PLA2s in spinal sensitization. We first demonstrate the presence of constitutive ...
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ژورنال
عنوان ژورنال: Neuroscience
سال: 2005
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2005.01.024